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PRESS RELEASE - 28 Oct 2013

Path-breaking stem cell transplant for eye, using a nano-sheet

Japanese nanotech institute and Indian ophthalmologists jointly accomplish with NCRM;
The next step towards a clinical translation to help corneal blindness patients

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Chennai, 28 Oct 2013: Using a nano-composite gel sheet developed by Kawamura Institute of Chemical Research, Japan, the scientists at NCRM and Ophthalmologists at Light Eye Hospital, Dharmapuri have successfully transplanted lab grown corneal endothelial precursor-stem cells to a bull’s eye in a simple and reproducible methodology paving way for future transplantation of one cadaver-eye derived corneal stem cells multiplied and be applicable in more than one patient’s eye. This work has been published in the journal“Current Eye Research”. (http://www.ncbi.nlm.nih.gov/pubmed/24144454)

Earlier, lab grown corneal endothelial stem cells have been transplanted to animal eyes with simple injection and eye-fixed position for 36 Hrs which is practically not feasible in patients. This methodology using a chemically synthesized nano-composite sheet makes things safer without biological contamination and also easy to accomplish clinically without the need for an eye-down position, said Dr Parikumar, Consultant Ophthalmologist. Previously we had proven that it is possible to transport the cells without cool preservation using a polymer scaffold (http://www.ijo.in/preprintarticle.asp?id=116457) and now this successful feat of the animal-eye transplantation makes us closer to bed side he added.


*"Nichi" stands for Japan and "In" stands for India. This institute started on an Indo-Japan collaboration now has spreaded further with global alliances
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